info@aliah.ac.in        

Department of  BIOLOGICAL SCIENCES


  Announcement


Dr Safdar Ali Assistant Professor / BIOLOGICAL SCIENCES

Email : ali@aliah.ac.in

Address : Clinical and Applied Genomics (CAG) Lab, IIA/27 Aliah University, Newtown Kolkata 700160

Room No : Faculty Room, 8th Floor Left Block

Joined : 20/09/2017

Clinical and Applied Genomics (CAG) Lab

My research groups focus has been viral genomics at two levels. First, the analysis of repeat sequences or microsatellites which are present as a unique signature in each genome. They are distributed ubiquitously across coding and non coding regions and exploring their impact on genome function, regulation and evolution forms the essence of our groups' work. The viral genome provides for an unique candidate for comparative, functional and evolutionary genomics owing to its relatively small size, high mutation rate and rapid evolutionary aspects. The second aspect has been understanding the evolution of SARS-CoV-2 through pholo-geo-network analyses and deciphering clinical correlations with sequence alterations at the protein level. 

Further, we are also exploring the interplay of various factors related to arsenic genotoxicity. 

 

Please visit my perosnal website for more details

https://sites.google.com/view/safdar/home

Courses Taught/Teaching

Bacteriology

Biophysics

Cell Biology

Computational Biology and Drug Design

Development Biology

Genetics and Genomics

Introduction to Microbiology 

Medical Microbiology

Molecular Biology  

Virology

Journal Papers Published

Recent Publications 

2022

  1. Laskar R; Jilani MG; Ali S (2022) Microsatellite Signature of Reference Genome Sequence of SARS-CoV-2 and 32 Species of Coronaviridae Family. Int J Infect. 9(2):e122019. https://dx.doi.org/10.5812/iji-122019
  2. Jilani MG; Ali S (2022) Assessment of simple sequence repeats signature in Hepatitis E virus (HEV) genomes J Genet Eng Biotechnol 2073. https://doi.org/10.1186/s43141-022-00365-w
  3. Samanta, A., Alam, S. S. M., Ali, S., & Hoque, M. (2022). Analyzing the interaction of human ACE2 and RBD of spike protein of SARS-CoV-2 in perspective of Omicron variant. EXCLI Journal21, 610-620. https://doi.org/10.17179/excli2022-4721

 

 

2021

  1. Nasrin T and Ali S (2021) Genetic Path of the Emergence of SARS-CoV-2. Gene Cell and Tissue 9(2):e118302. ISSN: 2345-6841.  DOi https://dx.doi.org/10.5812/gct.118302
  2. Laskar R and Ali S. (2021) Differential mutation profile of SARS-CoV-2 proteins across deceased and asymptomatic patients.        Chemico Biological Interactions ISSN: 0009-2797 DOI: doi.org/10.1016/j.cbi.2021.109598    https://www.scopus.com/sourceid/24652  IF 2021: 5.1
  3. Laskar R and Ali S. (2021) Phylo-geo-network and haplogroup analysis of 611 novel Coronavirus (SARS-CoV-2) genomes from India. Life Science Alliance 4(5): e202000925. DOI https://doi.org/10.26508/lsa.202000925 ISSN 2575-1077 https://www.scopus.com/sourceid/21100887409Citations 3 (Google Scholar). IF 2021: 4.6
  4. Laskar R and Ali S. (2021) Mutational analysis and assessment of its impact on proteins of SARS-CoV-2 genomes from India. Gene 778:145470. DOI: https://doi.org/10.1016/j.gene.2021.145470 ISSN: 0378-1119.  https://www.scopus.com/sourceid/15636IF 2021:3.7
  5. Laskar R, Jilani MG, Ali S (2021) Implications of genome simple sequence repeats signature in 98 Polyomaviridae species. 3 Biotech. 11(1): 35. Doi: 10.1007/s13205-020-02583-w.ISSN2190-5738 https://www.scopus.com/sourceid/21100447128IF 2021:2.4

 



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