Department of

BIOLOGICAL SCIENCES

  Announcement

Dr Md Zakir Hossain Assistant Professor / BIOLOGICAL SCIENCES

Email : zakirmd@aliah.ac.in

Address : Department of Biological Sciences Aliah University, 8th Floor New Town, Kolkata- 700160

Joined : 28/11/2017

Prior to joining Aliah University, I was associated with West Bengal Education Services as an Assistant Professor of Zoology and served Darjeeling Govt College, Darjeeling and SBS Govt College, Hili.

I believe in both imparting quality education along with preparing a student for job or research based on their interest and need. Along with teaching, I am also working with my colleagues in developing this department from a scratch into a top class institute for learning and research in the field of Biological Sciences.

I did my PhD from CSIR-CDRI, Lucknow & JNU, New Delhi with work based on animal modelling, Diabetes and its hormonal regulation. Currently my research interest is varied depending upon resources available and the interest of the research scholar. Along with Diabetes, I am working on Disease Biology, and Environmental Sciences. 

Education

Ph.D (2012-2017)

CSIR-CDRI, Lucknow and JNU, New Delhiunder the supervision of Dr. JR Gayen. Thesis entitled “Development and elucidation of mechanism of action of Pancreastatin inhibitor(s) to control Diabetes”.

B.Ed. (2010-2011)

Govt College of Teachers Education, Banipur, N/24/Parganas, West Bengal

M. Sc. Zoology (2007-2009)

PG Dept of Zoology, Tilka Manjhi University, Bhagalpur, Bihar

B. Sc. Zoology (2004-2007)

Bhagalpur National College, Tilka Manjhi University, Bhagalpur, Bihar

Schooling:

The Saint Xaviers School, Malda (Class XII)

Emmanuel English School, Samsi, Malda (Class X)

Teaching Experience

Assistant Professor in Dept of Biological Sciences

Aliah University, New Town, Kolkata-700160 (Nov, 2017 onwards)

Assistant Professor & HOD  in Dept of Zoology, SBS Govt College

Hili, D/Dinajpur-733126 (July, 2016 to Nov, 2017)

Assistant Professor in Dept of Zoology, Darjeeling Govt College

Darjeeling-734101 (April. 2015 to July, 2016)

Research Scholar at Pharmacokinetics & Metabolism Division

CSIR-CDRI, Lucknow-226031 (Jan, 2012 to April, 2015)

PGT in Biology, Raja Bijoy Singh Vidyamandir

Jiaganj, WB-742113 (Sep, 2011 to Jan, 2012)

Field of Specialization

MSc Speialization- Zoology (Cytogenetics)

PhD- Area of work : Diabetes and Endocrinology

Courses Taught/Teaching

Zoology- Animal Diversity, Ecology, Economic Zoology

Endocrinology, Genetics, Biochemistry, Biostatistics

 

Research Area

The research focus of our laboratory spans key areas of Lifesciences, Earth Science, and Disease Biology; aimed at understanding the complex interplay between animals, environment, and different human diseases. In diseases we aim to investigate the biology of different disease specially Diabetes, Cancer and Mental Health with special focus on pharmacology and Community Health involving common people and students. In Life Sciences, we explore animal physiology and biodiversity; studying how environmental changes influence species interactions and adaptation mechanisms. Our work in Earth Science investigates ecosystem health, particularly how anthropogenic impacts—such as pollution, habitat destruction, and climate change—affect ecological balance and biodiversity.

Conference Papers Published

1. Presented a paper entitled “Exercise with diabetic medication improves glucose homeostasis better than the drugs alone in STZ induced diabetic rats” at International Conference of Faunal diversity & Management held in Lucknow University, Lucknow, 2014

2. Presented a paper entitled “Proper and sound sleep may be the best beauty treatment” at a national seminar on recent trends in life sciences organised by Raiganj University, Raiganj, 2017

3. Presented a paper entitled “Deleterious effect of oxidative stress can be counteracted by exogenous antioxidants and contribute to diabetes regulation” at International Symposium on Chemistry for Human Welfare, organised by University of Gour Banga, Malda, 2017

Journal Papers Published

1. Chakraborty J, Hossain Z, Tripathi A, Ghosh W, and Samanta TB. Taxonomical characterization of a penicillin amidase producing novel strain of Achromobacter xylosoxidans: Proposal of A. xylosoxidans subsp. indiges subsp. Developmental Microbiology and Molecular Biology 3-1: 55-65, 2012

2. Valicherla GR, Hossain Z, Mahata SK, and Gayen JR. Pancreastatin is an endogenous peptide that regulates glucose homeostasis. Physiological genomics 45: 1060-1071, 2013.

3. Singh AK, Joharapurkar AA, Khan MP, Mishra JS, Singh N, Yadav M, Hossain Z, Khan K, Kumar S, and Dhanesha NA, Mishra DP, Maurya RK, Sharma S, Jain MR, Trivedi AK, Godbole MM, Gayen JR, Chattopadhyay N, Sanyal S. Orally Active Osteoanabolic Agent GTDF Binds to Adiponectin Receptors, With a Preference for AdipoR1, Induces Adiponectin-Associated Signaling, and Improves Metabolic Health in a Rodent Model of Diabetes. Diabetes 63: 3530-3544, 2014.

4. Goel A, Umar S, Nag P, Sharma A, Kumar L, Hossain Z, Gayen JR, and Nazir A. A dual colorimetric-ratiometric fluorescent probe NAP-3 for selective detection and imaging of endogenous labile iron (III) pools in C. elegans. Chemical Communications 51: 5001-5004, 2015.

5. Yadav NK, Saini KS, Hossain Z, Omer A, Sharma C, Gayen JR, Singh P, Arya K, and Singh R. Saraca indica Bark Extract Shows In Vitro Antioxidant, Antibreast Cancer Activity and Does Not Exhibit Toxicological Effects. Oxidative medicine and cellular longevity 2015: 2015.

6. Arya RK, Singh A, Yadav NK, Cheruvu SH, Hossain Z, Meena S, Maheshwari S, Singh AK, Shahab U, and Sharma C, Singh K, Narender T, Mitra K, Arya KR, Singh RK, Gayen JR, Datta D. Anti-breast tumor activity of Eclipta extract in-vitro and in-vivo: novel evidence of endoplasmic reticulum specific localization of Hsp60 during apoptosis. Scientific reports 5: 2015.

7. Pal S, Khan K, China SS, Mittal M, Porwal K, Srivastav R,Taneja I, Hossain Z, Mandalapu D, Gayn JR, Wahajuddin M, Sharma VL, Trivedi AK, Sanyal S, Bhadauria S, Godbole MM, Gupta SK, Chattopadhyay N. Theophylline, a methylxanthine drug induces osteopenia and alters calciotropic hormones, and prophylactic vitamin D treatment protects against these changes in rats. Toxicology and Applied Pharmacology 2015

8. Rajan S, Shankar K, Beg M, Varshney S, Gupta A, Srivastava A, Kumar D, Mishra RK, Hossain Z, Gayen JR, Gaikwad AN. Chronic hyperinsulinemia reduces insulin sensitivity and metabolic functions of brown adipocytes. Journal of Endocrinology 2016

9. NK Yadav, RK Arya, K Dev, C Sharma, Z Hossain, S Meena, KR Arya, JR Gayen, D Datta, RK Singh; Alcoholic extract of Eclipta alba shows in vitro antioxidant and anticancer activity without exhibiting toxicological effects. 2017; Oxidative medicine and cellular longevity, Volume 79 (7), Pages 339-351. https://doi.org/10.1155/2017/9094641

10. Singh S, Valicherla GR, Joshi P, Sudhir S, Anees S, Gupta A, Hossain Z, Italiya K, Makadia V, Singh SK, Wahajuddin M, Gayen JR. Determination of Permeability, Pasma Protein Binding, Blood Partitioning, Pharmacokinetics and Tissue Distribution of Withanolide A in rats: A Neuroprotective Steroidal Lactone. Drug Development Research 2018

11. HS Cheruvu, NK Yadav, GR Valicherla, RK Arya, Z Hussain, C Sharma, KR Arya, RK Singh, D Datta, JR Gayen. LC-MS/MS method for the simultaneous quantification of luteolin, wedelolactone and apigenin in mice plasma using hansen solubility parameters for liquid-liquid extraction. 2018; Journal of Chromatography B, Vol 1081-82, Pages 76-86. https://doi.org/10.1016/j.jchromb.2018.01.035

12. SK Singh, GR Valicherla, P Joshi, S Shahi, AA Syed, AP Gupta, Z Hossain, K Italiya, V Makadia, SK Singh, M Wahajuddin, JR Gayen. Determination of permeability, plasma protein binding, blood partitioning, pharmacokinetics and tissue distribution of Withanolide A in rats: A neuroprotective steroidal lactone. 2018; Drug development research, Volume 79 (7), Pages 339-351. https://doi.org/10.1002/ddr.21463

13. Z Hossain, GR Valicherla, AP Gupta, AA Syed, M Riyazuddin, S Chandra, MI Siddiqi, JR Gayen. Discovery of pancreastatin inhibitor PSTi8 for the treatment of insulin resistance and diabetes: studies in rodent models of diabetes mellitus. 2018; Scientific reports 8:8715. https://doi.org/10.1038/s41598-018-27018-8

14. AP Gupta, P Singh, R Garg, GR Valicherla, M Riyazuddin, Anees A.Syed, Z Hossain, JR Gayen; Pancreastatin inhibitor activates AMPK pathway via GRP78 and ameliorates dexamethasone induced fatty liver disease in C57BL/6 mice. 2019; Biomedicine & Pharmacotherapy; Volume 116. https://doi.org/10.1016/j.biopha.2019.108959

15. GR Valicherla, AP Gupta, Z Hossain, M Riyazuddin, AA Syed, A Husain, S Lahiri, KM Dave, JR Gayen. Pancreastatin inhibitor, PSTi8 ameliorates metabolic health by modulating AKT/GSK-3β and PKCλ/ζ/SREBP1c pathways in high fat diet induced insulin resistance in peri-/postmenopausal rats. 2019; Peptides, Volume 120. https://doi.org/10.1016/j.peptides.2019.170147.

16. SK Singh, GR Valicherla, AK Bikkasani, SH Cheruvu, Z Hossain, I Taneja, H Ahmad, KSR Rajua, NS Sangwan, SK Singh, AK Dwivedi, M Wahajuddin, JR Gayen. Elucidation of plasma protein binding, blood partitioning, permeability, CYP phenotyping and CYP inhibition studies of Withanone using validated UPLC method: An active constituent of neuroprotective herb Ashwagandha. 2021; Journal of Ethnopharmacology Volume 270. https://doi.org/10.1016/j.jep.2021.113819

17. T Ahamed, Zakir Md Hossain. Fresh water fish diversity with their conservation status in Kolkata fish markets. 2022; Indian Journal of Applied & Pure Biology 11/2022.

18. S Mohinuddin, S Sengupta, B Sarkar, UD Saha, A Islam, ARMT Islam, ZM Hossain, S Mahammad, T Ahamed, R Mondal, W Zhang & A Basra. Assessing lake water quality during COVID-19 era using geospatial techniques and artificial neural network model. 2023; Environmental Science and Pollution Research; Vol- 30, Pages 65848–65864. https://doi.org/10.1007/s11356-023-26878-6

19. P Laskar , S Ganguly, ZM Hossain. Assessing the Change in Psychosocial Stress of Fireworks Workers of West Bengal During the Pre-Pandemic and During COVID-19 Pandemic. 2023; Journal of Ecophysiology and Occupational Health, Vol 23(2), 82-88. DOI 10.18311/jeoh/2023/33112.

20. P Laskar , S Ganguly, ZM Hossain. Cross-sectional study on Lipid profile and Haematological parameters among fireworks workers in West Bengal, India. 2023; Indian Journal of Applied & Pure Biology.

Books Published

1. Book Chapter entitled 'Effects of Covid-19 on Biodiversity and Conservation' in the book- Pathos of Pandemic, Covid-19, New Delhi Publisher (ISBN: 97893 93878 007), 2022

Awards

1) Best Poster Presentation Award in Health Science group in International Conference Faunal diversity & Management held in Lucknow University, Lucknow, 2014

2) Incentive Award for best research & publication from CSIR-CDRI, Lucknow, 2014

3) Qualified CSIR-UGC NET JRF (2010, 2011), GATE (2010)

Ph.D. Thesis Guidance

1. Payel Laskar (BIO181605)
Thesis submitted, titled- Occupational Health Hazards of Fireworks Workers in West Bengal.
2. Taushik Ahamed (BIO181601)
Working on water pollution in ground and surface water in/around Kolkata

Patents

Patents Filed

1. Synthesised peptides acting as possible pancreastatin inhibitors and able to control diabetes by Gayen JR, Valicherla GR, Hossain Z, Gupta AP, Ahmed SA, Mohammed R, Siddiqi MI, Chandra S, filing number BD-IPU/PAT/01/2016 dated 08/01/2016

2. Substituted Naptho(2,1-b)(1,10)phenanthronile-based fluorescent dyes and application thereof by Goel A, Umar S, Nag P, Nazir A, Kumar L, Shamsuzzama, Gayen JR, Hossain Z filing number DSTM/PAT/07/2014 dated 20/03/2014

Invited Lectures

  1. Organized an Invited lecture on Growing clutches of Cancer and means to prevent it at SBS Govt College, Hili on 28/08/2017

Membership Of Learned Societies

1. Life time member of Laboratory Animal Science Association of India (LASAI)
2. Indian Science Congress, Kolkata.

Orientation/Refresher/QIP CourseAttended/Organized

1. Participated in Scientific and Technical Awareness Programme on Animal Experimentation held at Division of Laboratory Animals, CDRI, Lucknow from March 26-30, 2012.

2. Participated in Hands on Training Workshop on Microbial Tools and Techniques from March 3-7, 2017; organized by Dept of Zoology, University of Gour Banga, Malda.

3. Attended Academic Leadership Programme from April 16-19, 2018; organized by CALEM and Aligarh Muslim University Murshidabad Centre at Jangipir Campus.
4. Attended 123rd UGC Sponsored Orientation Programme of  UGC-HRDC, Calcutta University, Kolkata from 4th Sep, 2018 to 3rd Oct, 2018.

5. Participated in Science Academies' Refresher Course: Foundation in Plant and Animal Biology, from 01.02.19 to 16.02.19 organised by Indian Science Academies and CAS, Botany, Madras University, 2019
6. Completed Science Academies' Science Leadership Workshop by Central University of Punjab, Bathinda from 22nd to 28th June, 2020

7. Attended FDP on Analysis of Drinking Water Quality Parameters organized by NITTTR, Kolkata from 8th to 12th November, 2021

8. Participated in Virtual workshop and Hands on Training on Next Genereation Bioinformatics Approaches in Infection Biology; imparted by Jaypee Institute of Information Technology, Noida from 4th to 15th April, 2022

9. Attended STC on Statistical Analysis using various softwares organized by NEHU-HRDC, Shillong from 21st to 27th September, 2022

Consultancy work / Testing

Founding member of The Foot Print’s Organization- A social body for upliftment and empowerment of people via education in Malda, WB




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